Bakherad, Mohammad; Keivanloo, Ali; Mohammadi, Marzieh; Jajarmi, Saeideh published an article in Letters in Organic Chemistry. The title of the article was 《Syntheses of 2-benzyl substituted imidazo[1,2-a]pyrimidines via coupling-cyclization under Pd-Cu catalysis》.Product Details of 41252-95-3 The author mentioned the following in the article:
The reaction of 1-(prop-2-yn-1-yl)pyrimidin-2(1H)-imine with various halobenzenes in the presence of a palladium catalyst leads to the production of 2-benzyl substituted imidazo[1,2-a]pyrimidines, e.g. I (R = 4-O2N, 2-O2N-4-Cl, 4-MeCO).1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Product Details of 41252-95-3) was used in this study.
1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Product Details of 41252-95-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com