Wu, Dan; Hao, Wen-Juan; Rao, Qian; Lu, Yi; Tu, Shu-Jiang; Jiang, Bo published an article in 2021. The article was titled 《Engaging 1,7-diynes in a photocatalytic Kharasch-type addition/1,5-(SN”)-substitution cascade toward β-gem-dihalovinyl carbonyls》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).COA of Formula: C6H4ClI The information in the text is summarized as follows:
A new and general photocatalytic Kharasch-type addition/1,5-(SN”)-substitution cascade of 1,7-diynes with alkyl halides such as BrCCl3 and CBr4 was reported for the first time, and used to produce 65 hitherto unreported β-gem-dihalovinyl ketones/aldehydes with moderate to excellent yields in a highly regioselective manner. This reaction tolerates a wide scope of substrates, which offers a green and efficient entry to fabricate synthetically important β-gem-dihalovinyl carbonyl scaffolds. Notably, the late-stage application of these resulting β-gem-dihalovinyl carbonyls shows high and unique reactivity profiles and demonstrates the versatility of their derivatization. Thus, e.g., treatment of diyne I with CBrCl3 under blue irradiation in presence of fac-Ir(ppy)3 and NaOAc base in EtOH afforded II (80%). In the experiment, the researchers used many compounds, for example, 1-Chloro-3-iodobenzene(cas: 625-99-0COA of Formula: C6H4ClI)
1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.COA of Formula: C6H4ClI
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com