In 2022,Teixeira Campos, Patrick; Karkow Bones, Mariana; Siqueira da Silva, Rubia Mara published an article in European Journal of Organic Chemistry. The title of the article was 《Energetic and Topological Supramolecular Study and Nucleation Mechanism Proposal of Halogenated Phenols》.HPLC of Formula: 626-02-8 The author mentioned the following in the article:
In this work, an energetic and topol. supramol. study of 10 different halogenated phenols, X-C6H4-OH (X=F, Cl, Br and I) in the ortho, meta, and para positions was carried out, except for X=Br, in ortho- and meta-X-phenols. Most compounds have a mol. coordination number (MCN) of fourteen. All intermol. interactions were classified, and the robustness was evaluated. Strong intermol. interactions such as O-H···O and π···π contributed half the energy of the cluster, although interactions considered weak as C-H···X and C-H···π reached 40% in energetic contribution, as they revealed a greater number of occurrences. Addnl., these theor. data of energy were correlated with exptl. data of m.p. and packing d. revealing a notable trend. In almost all cases evaluating the same position, the higher the d., the higher the m.p. and the higher the stabilizing energy. Finally, nucleation proposals were suggested for all compounds and revealed that six compounds needed three stages, while four compounds needed only two stages to promote the growth of the supramol. structure in three directions. In the experimental materials used by the author, we found 3-Iodophenol(cas: 626-02-8HPLC of Formula: 626-02-8)
3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.HPLC of Formula: 626-02-8
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com