Tang, Shi; Ding, Shumin; Li, Dan; Li, Lianjie; Zhao, Haixia; Chai, Minxue; Wang, Jian published an article in 2021. The article was titled 《Palladium-catalysed imidoylative spirocyclization of 3-(2-isocyanoethyl)indoles》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Formula: C7H5IO The information in the text is summarized as follows:
A palladium-catalyzed construction of spiroindolines through dearomative spirocyclization of 3-(2-isocyanoethyl)indoles was developed. 2′-Aryl-, vinyl-, and alkyl-substituted spiroindolines were accessed under mild conditions with excellent functional group tolerance. C1-tethered oxindole- and indole-spiroindoline bisheterocycles were generated in high yields via alkene/allene insertion and an imidoylative spirocyclization cascade. Addnl., a tandem dearomatization of two different indoles was realized with N-(2-bromobenzoyl)indoles as the electrophilic coupling partner of 3-(2-isocyanoethyl)indoles, affording polyindoline – spiroindoline bisheterocyclic scaffolds conveniently. Under the catalysis of Pd(OAc)2 and a spinol-derived phosphoramidite ligand, chiral spiroindolines were successfully accessed with up to 95% yield and 85% ee. In the part of experimental materials, we found many familiar compounds, such as 4-Iodobenzaldehyde(cas: 15164-44-0Formula: C7H5IO)
4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Formula: C7H5IO
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com