In 2018,Soulard, Valentin; Villa, Giorgio; Vollmar, Denis Patrick; Renaud, Philippe published 《Radical Deuteration with D2O: Catalysis and Mechanistic Insights》.Journal of the American Chemical Society published the findings.Recommanded Product: 301673-14-3 The information in the text is summarized as follows:
N-Dodecanethiol acts as a catalyst for the chemoselective radical deuteration of alkyl iodides with D2O initiated by dry air and Et3B. The method is compatible with a wide range of functional groups and provides the monodeuterated products in good yields and with a high level of deuterium incorporation. A revised mechanism for the deoxygenation of xanthates using alkylboranes and water (Wood deoxygenation) is proposed involving dialkylthioborinates as intermediates; n-C12H25SBEt2 is prepared and found to be a competent catalyst for radical deuteration of an alkyl iodide in the absence of thiol. The experimental part of the paper was very detailed, including the reaction process of tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Recommanded Product: 301673-14-3)
tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Recommanded Product: 301673-14-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com