Force, Guillaume; Perfetto, Anna; Mayer, Robert J.; Ciofini, Ilaria; Leboeuf, David published an article in 2021. The article was titled 《Macrolactonization Reactions Driven by a Pentafluorobenzoyl Group》, and you may find the article in Angewandte Chemie, International Edition.Related Products of 626-02-8 The information in the text is summarized as follows:
Macrolactones constitute a privileged class of natural and synthetic products with a broad range of applications in the fine chems. and pharmaceutical industry. Despite all the progress made towards their synthesis, notably from seco-acids, a macrolactonization promoter system that is effective, selective, flexible, readily available, and, insofar as possible, compatible with manifold functional groups is still lacking. Herein, we describe a strategy that relies on the formation of a mixed anhydride incorporating a pentafluorophenyl group which, due to its high electronic activation enables a convenient access to macrolactones, macrodiolides and esters with a broad versatility. Kinetic studies and DFT computations were performed to rationalize the reactivity of the pentafluorophenyl group in macrolactonization reactions. The experimental part of the paper was very detailed, including the reaction process of 3-Iodophenol(cas: 626-02-8Related Products of 626-02-8)
3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Related Products of 626-02-8 Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com