In 2019,Angewandte Chemie, International Edition included an article by Diehl, Claudia J.; Scattolin, Thomas; Englert, Ulli; Schoenebeck, Franziska. Synthetic Route of C6H4BrI. The article was titled 《C-I-Selective Cross-Coupling Enabled by a Cationic Palladium Trimer》. The information in the text is summarized as follows:
While there is a growing interest in harnessing synergistic effects of more than one metal in catalysis, relatively little is known beyond bimetallic systems. This report describes the straightforward access to an air-stable Pd trimer and presents unambiguous reactivity data of its privileged capability to differentiate C-I over C-Br bonds in C-C bond formations (arylation and alkylation) of polyhalogenated arenes, which typical Pd0 and PdI-PdI catalysts fail to deliver. Exptl. and computational reactivity data, including the first location of a transition state for bond activation by the trimer, are presented, supporting direct trimer reactivity to be feasible. In addition to this study using 1-Bromo-3-iodobenzene, there are many other studies that have used 1-Bromo-3-iodobenzene(cas: 591-18-4Synthetic Route of C6H4BrI) was used in this study.
1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Synthetic Route of C6H4BrI Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com