In 2018,Chen, Jia; Lin, Jin-Hong; Xiao, Ji-Chang published 《Dehydroxylation of alcohols for nucleophilic substitution》.Chemical Communications (Cambridge, United Kingdom) published the findings.Computed Properties of C2H4I2 The information in the text is summarized as follows:
The Ph3P/ICH2CH2I system-promoted dehydroxylation and subsequent nucleophilic substitution of alcs. with various nucleophiles was achieved to afford amines/sulfanes/ethers/halides via C-O, C-N, C-S and C-X (X = Cl, Br, and I) bond formation. Compared with the previous approaches such as the Appel and Mitsunobu reactions, this protocol offered some practical advantages such as safe operation and a convenient amination process. The experimental process involved the reaction of 1,2-Diiodoethane(cas: 624-73-7Computed Properties of C2H4I2)
1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Computed Properties of C2H4I2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com