Sviripa, Vitaliy M’s team published research in Bioorganic & Medicinal Chemistry Letters in 2014-08-01 | 2265-92-1

Bioorganic & Medicinal Chemistry Letters published new progress about Antiproliferative agents. 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, Recommanded Product: 1,4-Difluoro-2-iodobenzene.

Sviripa, Vitaliy M.; Zhang, Wen; Kril, Liliia M.; Liu, Alice X.; Yuan, Yaxia; Zhan, Chang-Guo; Liu, Chunming; Watt, David S. published the artcile< Halogenated diarylacetylenes repress c-myc expression in cancer cells>, Recommanded Product: 1,4-Difluoro-2-iodobenzene, the main research area is halogenated diarylacetylene preparation cmyc inhibitor cancer; Antineoplastic agents; Colon cancer; Diarylacetylenes; c-myc.

Halogenated diarylacetylenes that possess fluorine or chlorine substituents in one aryl ring and N-methylamino or N,N-dimethylamino in the other aryl ring inhibit the proliferation of LS174T colon cancer cells through the repression of c-myc expression and induction of the cyclin-dependent kinase inhibitor-1 (i.e., p21(Wif1/Cip1)) and represent potentially useful antineoplastic agents.

Bioorganic & Medicinal Chemistry Letters published new progress about Antiproliferative agents. 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, Recommanded Product: 1,4-Difluoro-2-iodobenzene.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com