The author of 《Photooxygenation inhibits tau amyloid formation》 were Suzuki, Takanobu; Hori, Yukiko; Sawazaki, Taka; Shimizu, Yusuke; Nemoto, Yu; Taniguchi, Atsuhiko; Ozawa, Shuta; Sohma, Youhei; Kanai, Motomu; Tomita, Taisuke. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Safety of 1-Iodopyrrolidine-2,5-dione The author mentioned the following in the article:
Tau amyloid formation and deposition are responsible for the onset of Alzheimer’s disease. In particular, the seeding activity of the tau protein plays an important role in the spreading of tau pathol. via its propagation in the human brain. Here we demonstrate that catalytic photo-oxygenation markedly suppresses tau seeding activity, resulting in the inhibition of amyloid formation, both in vitro and in cultured cells. In the part of experimental materials, we found many familiar compounds, such as 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Safety of 1-Iodopyrrolidine-2,5-dione)
1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Safety of 1-Iodopyrrolidine-2,5-dione
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com