SDS of cas: 625-99-0In 2022 ,《Enantioselective C-H bond functionalization of aromatic ketones with 1,6-enynes via photoredox/cobalt dual catalysis》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Maji, Kakoli; Thorve, Pradip Ramdas; Rai, Pramod; Maji, Biplab. The article conveys some information:
An enantioselective ortho-C(sp2)-H functionalization of ketones/esters, e.g., I (R1 = Me, Et, Ph, OMe; R2 = H, 4-F, 3-MeO, 3,4-benzo, etc.) with 1,6-enynes II [Ar = Ph, X = NTs, O, C(COOMe)2; Ar = 3-ClC6H4, 4-MeOC6H4, 3,5-Me2C6H3, etc., X = NTs] is demonstrated via photoredox/cobalt dual catalysis. The method provides the corresponding arylmethylene-substituted carbo- and heterocycles III in high yields with functional group tolerance and selectivity. Mechanistic studies suggested the operation of visible-light mediated low-valent cobalt complex generation, intramol. cyclization, ortho-C-H bond insertion, and reductive elimination as the key mechanistic steps. The experimental process involved the reaction of 1-Chloro-3-iodobenzene(cas: 625-99-0SDS of cas: 625-99-0)
1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides.SDS of cas: 625-99-0 The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com