The author of 《Pd-Catalyzed Heterocyclization During Sonogashira Coupling: Synthesis of 3-Aryl-substituted Imidazo[2,1-b]thiazoles》 were Bakherad, Mohammad; Keivanloo, Ali; Nasr-Isfahani, Hossein; Raeissi, Mersad. And the article was published in Phosphorus, Sulfur and Silicon and the Related Elements in 2011. Reference of 1-Chloro-4-iodo-2-nitrobenzene The author mentioned the following in the article:
The reaction of 4,5-diphenyl-2-propargylmercaptoimidazole with various aryl iodides catalyzed by Pd-Cu in the presence of triethylamine as base in DMF leads to the formation of 3-aryl-substituted imidazo[2,1-b]thiazoles, e.g, I. In the experiment, the researchers used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Reference of 1-Chloro-4-iodo-2-nitrobenzene)
1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Reference of 1-Chloro-4-iodo-2-nitrobenzene Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com