Huang, Shengli’s team published research in Organic & Biomolecular Chemistry in 2019 | 2265-92-1

Organic & Biomolecular Chemistry published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, SDS of cas: 2265-92-1.

Huang, Shengli; Chen, Zhili; Mao, Hui; Hu, Fangli; Li, Dongmei; Tan, Yu; Yang, Fengqing; Qin, Wenling published the artcile< Metal-free difunctionalization of alkynes to access tetrasubstituted olefins through spontaneous selenosulfonylation of vinylidene ortho-quinone methide (VQM)>, SDS of cas: 2265-92-1, the main research area is selenovinyl sulfone regioselective diastereoselective preparation; alkynylnaphthol selenosulfonylation selenosulfonate.

A metal-free difunctionalization of alkynes to access tetrasubstituted olefins through spontaneous selenosulfonylation of vinylidene ortho-quinone methide (VQM) was described herein. The reaction was conducted under mild conditions without any catalysts or additives. Preliminary mechanism studies revealed that the formation of VQM was the key for this alkyne di-functionalization reaction. The reaction could be applied in the enantioselective asym. synthesis of axially chiral styrene. Furthermore, the selenosulfonylation adducts can be transformed into useful naphtho[2,1-b]furan and benzofuran scaffolds.

Organic & Biomolecular Chemistry published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 2265-92-1 belongs to class iodides-buliding-blocks, and the molecular formula is C6H3F2I, SDS of cas: 2265-92-1.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com