Cabrita, Ivania; Fernandes, Ana C. published the artcile< A novel efficient and chemoselective method for the reduction of nitriles using the system silane/oxo-rhenium complexes>, Application In Synthesis of 887266-99-1, the main research area is rhenium catalyzed reduction nitrile reactant primary amine preparation; oxo rhenium catalyzed reduction nitrile reactant amine preparation.
This work reports the reduction of nitriles to the corresponding primary amines, e.g. 4-I-3-FC6H3CH2NH2 and 4-MeSC6H4CH2NH2, with silanes catalyzed by oxo-rhenium complexes. The catalytic system PhSiH3/ReIO2(PPh3)2 (10 mol %) reduced efficiently a series of nitriles in the presence of a wide range of functional groups such as -Cl, -F, -Br, -I, -CF3, -OCH3, -SCH3, -SO2CH3 and -NHTs.
Tetrahedron published new progress about Nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 887266-99-1 belongs to class iodides-buliding-blocks, and the molecular formula is C7H3FIN, Application In Synthesis of 887266-99-1.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com