Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. HPLC of Formula: 5029-67-4.
Li, Xiong;Xu, Jie;Li, Yue;Kramer, Soeren;Skrydstrup, Troels;Lian, Zhong research published 《 Silylcarboxylic Acids as Bifunctional Reagents: Application in Palladium-Catalyzed External-CO-Free Carbonylative Cross-Coupling Reactions》, the research content is summarized as follows. A palladium-catalyzed external-CO-free carbonylative Hiyama-Denmark cross-coupling reaction is presented. The introduction of silylcarboxylic acids I (R = 4-Me, 3-Me, 2-Me, 4-tert-butyl) as bifunctional reagents (CO and nucleophile source) avoids the need for external gaseous CO and a silylarene coupling partner. The transformation features high functional group tolerance and it is successful with electron-rich, -neutral, and -poor aryl iodides ArI (Ar = 4-methoxyphenyl, naphthalen-1-yl, thiophen-3-yl, etc.). Stoichiometric studies and control experiments provide insight into the reaction mechanism and support the hypothesized dual role of silylcarboxylic acids.
5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., HPLC of Formula: 5029-67-4
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com