Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Application of C5H4IN.
Landge, Vinod G.;Bonds, Audrey L.;Mncwango, Thandazile A.;Mather, Carolina B.;Saleh, Yasaman;Fields, Hunter L.;Lee, Frank;Young, Michael C. research published 《 Amine-directed Mizoroki-Heck arylation of free allylamines》, the research content is summarized as follows. The transition metal-catalyzed Mizoroki-Heck reaction is a powerful method to synthesize C-C bonds, allowing access to several important pharmaceuticals. Traditionally free amines have not been compatible with these approaches due to oxidation of the amine by the transition metal or other side reactions. However, the functionalization of unprotected allylamines is particularly attractive due to their prevalence in various biol. active mols. Herein, the palladium-catalyzed selective monoarylation of free allylamines using aryl iodides is reported. The strategy works on primary, secondary, and tertiary amines, making it very general. This monoarylation method is scalable and works on aryl iodides with a variety of substituted arene or heterocycle motifs, including chromophoric substrates.
1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Application of C5H4IN
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com