Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Quality Control of 1120-90-7.
Komiyama, K.;Kobayashi, S.;Shoji, T.;Kikushima, K.;Dohi, T.;Kita, Y. research published 《 Practical synthesis of diaryliodonium(III) triflates using ArI(OAc)2/TfOH/MeCN reaction system》, the research content is summarized as follows. Diaryliodonium(III) triflates Ar(Ar1)I+-OS(O)2CF3 (Ar = Ph, 2-bromophenyl, 2,4,6-trimethylphenyl, etc.; Ar1 = 4-methylphenyl, 4-methoxy-2-(methoxycarbonyl)benzen-1-yl, thiophen-2-yl, etc.) and 3-(p-tolyliodonio)pyridin-1-ium/3-(p-tolyliodonio)quinolin-1-ium bistriflates were synthesized in a safe manner by the reaction of aryliodine(III) diacetates ArI(OAc)2 and 3-(diacetoxyiodo)pyridine/3-(diacetoxyiodo)quinoline trifluoromethanesulfonic acids, aromatic compounds Ar1H with triflic acid (TfOH) in MeCN under mild exothermic conditions. This method provides access to a variety of diaryliodonium(III) triflates, including derivatives with two different aryl substituents, with high purity.
1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Quality Control of 1120-90-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com