In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. HPLC of Formula: 1120-90-7.
Guo, Shi-Yu;Yang, Fan;Song, Ting-Ting;Guan, Yu-Qing;Min, Xiang-Ting;Ji, Ding-Wei;Hu, Yan-Cheng;Chen, Qing-An research published 《 Photo-induced catalytic halopyridylation of alkenes》, the research content is summarized as follows. Here an atom-economical cross-coupling of halopyridines such as 2-chloropyridine, 2-iodopyridine, 2-bromo-6-methylpyridine, etc. and unactivated alkenes such as hex-1-ene, cyclopentene, ethenylcyclohexane, etc. under photo-redox catalysis to afford a series of alkene halopyridylation products e.g., I was reported. This protocol with mild and redox neutral conditions contributes broad substrate scope. As a complement to conventional Heck-type reaction, this radical process avoids the involvement of β-H elimination and thus useful pyridyl and halide groups could be simultaneously and regioselectively incorporated onto alkenes. The success depends on TFA-promoted domino photocatalytic oxidative quenching activation and radical-polar crossover pathway. Plausible mechanism is proposed based on mechanistic investigations. Moreover, the reserved C-X bonds of these products are beneficial for performing further synthetic elaborations.
1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., HPLC of Formula: 1120-90-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com