Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons-Smith reaction (cyclopropanation using iodomethane), 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction. Related Products of 1120-90-7.
Abaid, Kmar;Erb, William;Blot, Marielle;Roisnel, Thierry;Mongin, Florence;Touil, Soufiane research published 《 Ferrocenephosphonates: Copper-Promoted Synthesis and Further Functionalization》, the research content is summarized as follows. Phosphonylation of iodoferrocenes R1FcI with hydrophosphonates HP(O)(OR)2, catalyzed by CuI/DMEDA catalyst, afforded phosphonoferrocenes R1FcP(O)(OR)2 (R1 = H, 2-F, 2-CO2Me, 2-CH2OH, 2-CH2OMe; R = Et, iPr, Ph), which were further functionalized via directed lithiation-substitution protocol. Ferrocenephosphonates make up an important class of organometallic derivatives with a wide range of useful applications in organic synthesis and coordination chem. Here, an approach to ferrocenephosphonates based on a copper-promoted Hirao coupling is reported. Further functionalizations based on regioselective deprotolithiation and both Negishi and Suzuki-Miyaura cross-coupling reactions are also described to reach original derivatives
Related Products of 1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com