Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 2058236-52-3, is researched, Molecular C19H16N2O, about Enantioselective Palladium-Catalyzed Oxidative Cascade Cyclization of Aliphatic Alkenyl Amides, the main research direction is acrylamide heterocyclization stereoselective catalyst palladium pyrox preparation pyrrolizidinone; crystal structure pyrrolizidinone preparation stereoselective heterocyclization acrylamide transition state; mol structure pyrrolizidinone preparation stereoselective heterocyclization acrylamide transition state.Application of 2058236-52-3.
The catalyst system of Pd(TFA)2/(S,S)-diPh-pyrox is reported to promote the highly efficient enantioselective oxidative cascade cyclization of alkene-tethered aliphatic acrylamides under mild aerobic conditions. Pyrrolizidine derivatives were synthesized in good yield and excellent enantioselectivity. D-labeling experiments revealed that the reaction proceeded through an anti-aminopalladation (anti-AP) pathway with high selectivity. The transition states for the anti-AP step account for the observed enantioselectivity.
In addition to the literature in the link below, there is a lot of literature about this compound((S)-4-Benzyl-2-(isoquinolin-1-yl)-4,5-dihydrooxazole)Application of 2058236-52-3, illustrating the importance and wide applicability of this compound(2058236-52-3).
Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com