Safety of (2S)-(+)-3-Chloropropane-1,2-diol. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (2S)-(+)-3-Chloropropane-1,2-diol, is researched, Molecular C3H7ClO2, CAS is 60827-45-4, about A new practical synthesis of ethyl (R)-(-)-4-cyano-3-hydroxybutyrate from (S)-3-chloro-1,2-propanediol. Author is Jiang, Chengjun; Hong, Huabin.
A practical chem. synthesis of (R)-4-cyano-3-hydroxybutyrate was accomplished starting from (S)-3-chloro-1,2-propanediol, which is the main byproduct originating from (S,S)-salen Co(III)-catalyzed hydrolytic kinetic resolution of epichlorohydrin. The new synthetic approach demonstrated an efficient utilization of organic byproduct for the asym. synthesis of the intermediate of atorvastatin.
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Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com