Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 60827-45-4, is researched, Molecular C3H7ClO2, about Effects of the optical isomers of α-chlorohydrin on glycolysis by ram testicular spermatozoa and the fertility of male rats, the main research direction is chlorohydrin sperm glycolysis fertility.Safety of (2S)-(+)-3-Chloropropane-1,2-diol.
When 0.1 mM S-α-chlorohydrin [60827-45-4] was present in incubations, glycolysis by ram testicular spermatozoa was almost completely inhibited whereas 10 mM R-α-chlorohydrin [57090-45-6] had no effect. Male rats dosed orally with S-α-chlorohydrin (3.25 mg/kg/day) became much less fertile than controls but those dosed with R-α-chlorohydrin (13 mg/kg/day) did not. The loss of fertility was associated with a reduced ability of spermatozoa from the cauda epididymidis of these rats to oxidize glucose [50-99-7]. Apparently, the S enantiomer is responsible for both the inhibition of sperm glycolysis and the reduction in fertility caused by the racemic mixture of α-chlorohydrin.
In addition to the literature in the link below, there is a lot of literature about this compound((2S)-(+)-3-Chloropropane-1,2-diol)Safety of (2S)-(+)-3-Chloropropane-1,2-diol, illustrating the importance and wide applicability of this compound(60827-45-4).
Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com