Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Applied Microbiology and Biotechnology called A gram-negative bacterium producing a heat-stable nitrilase highly active on aliphatic dinitriles, Author is Gavagan, J. E.; DiCosimo, R.; Eisenberg, A.; Fager, S. K.; Folsom, P. W.; Hann, E. C.; Schneider, K. J.; Fallon, R. D., which mentions a compound: 4553-62-2, SMILESS is N#CC(C)CCC#N, Molecular C6H8N2, HPLC of Formula: 4553-62-2.
A Gram-neg. bacterial strain, identified as Acidovorax facilis strain 72W, has been isolated from soil by enrichment using 2-ethylsuccinonitrile as the sole nitrogen source. This strain grows on a variety of aliphatic mono- and dinitriles. Experiments using various heating regimes indicate that nitrile hydratase, amidase and nitrilase activities are present. The nitrilase is efficient at hydrolyzing aliphatic dinitriles to cyanoacid intermediates. It has a strong bias for C3-C6 dinitriles over mononitriles of the same chain length. Whole, resting cell hydrolysis of 2-methylglutaronitrile results in 4-cyanopentanoic acid and 2-methylglutaric acid as the major products. Heating, at least 20 min at 50°C, eliminates nitrile hydratase and amidase activities, resulting in greater than 97% selectivity to 4-cyanopentanoic acid. The nitrilase activity has good heat stability, showing a half-life of 22.7 h at 50°C and a temperature optimum of at least 65°C for activity. The strain has been deposited as ATCC 55746.
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Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com