Keller, Christopher L.; Dalessandro, James D.; Hotz, Richard P.; Pinhas, Allan R. published the article 《Reactions in Water: Alkyl Nitrile Coupling Reactions Using Fenton’s Reagent》. Keywords: alkyl nitrile Fenton reagent water coupling; dinitrile preparation green chem.They researched the compound: 2-Methylglutaronitrile( cas:4553-62-2 ).Electric Literature of C6H8N2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:4553-62-2) here.
The coupling reaction of water-soluble alkyl nitriles using Fenton’s reagent (Fe(II) and H2O2) is described. The best metal for the reaction is iron(II); and the greatest yields are obtained when the concentration of the metal is kept low. Hydrogen-atom abstraction is selective, preferentially producing the radical α to the nitrile. In order to increase the production of dinitrile, in situ reduction of iron(III) to iron(II), using a variety of reducing agents, was investigated.
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Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com