Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 60827-45-4, is researched, Molecular C3H7ClO2, about The action of (S)-α-chlorohydrin and 6-chloro-6-deoxyglucose on the metabolism of guinea pig spermatozoa, the main research direction is chlorohydrin sperm metabolism; chlorodeoxyglucose sperm metabolism; glycolysis sperm chlorohydrin chlorodeoxyglucose; lactate fructose sperm chlorohydrin chlorodeoxyglucose; fructose lactate sperm chlorohydrin chlorodeoxyglucose.Name: (2S)-(+)-3-Chloropropane-1,2-diol.
(S)-α-Chlorohydrin [60827-45-4] inhibited the conversion of D-fructose [57-48-7] to lactate [50-21-5] by mature guinea pig spermatozoa in vitro. At 2 mM, there was a specific inhibition of glyceraldehyde-phosphate dehydrogenase [9001-50-7], resulting in the accumulation of fructose 1,6-bisphosphate [488-69-7], dihydroxyacetone 3-phosphate [57-04-5], and glyceraldehyde 3-phosphate [591-59-3] and a concomitant decrease in the concentration of endogenous lactate. (R,S)-[3-36Cl]-α-chlorohydrin was metabolized by the spermatozoa to 3-chlorolactaldehyde [84709-24-0] of unknown configuration. Exogenous (R,S)-3-chlorolactaldehyde [84709-24-0] (2 mM) was an inhibitor of glyceraldehyde-phosphate dehydrogenase in guinea pig spermatozoa, whereas (R)-α-chlorohydrin [57090-45-6] (10 mM) had no significant effect on the metabolism of fructose. 6-Chloro-6-deoxyglucose [40656-44-8] (10 mM) inhibited glyceraldehyde-phosphate dehydrogenase in guinea pig spermatozoa in vitro and was metabolized to 3-chlorolactaldehyde which was presumably the (S)-isomer. The antiglycolytic actions of (S)-α-chlorohydrin and 6-chloro-6-deoxyglucose in guinea pig spermatozoa are probably due to the action of a common metabolite, (S)-3-chlorolactaldehyde [86747-03-7].
From this literature《The action of (S)-α-chlorohydrin and 6-chloro-6-deoxyglucose on the metabolism of guinea pig spermatozoa》,we know some information about this compound(60827-45-4)Name: (2S)-(+)-3-Chloropropane-1,2-diol, but this is not all information, there are many literatures related to this compound(60827-45-4).
Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com