Top Picks: new discover of 60827-45-4

There is still a lot of research devoted to this compound(SMILES:OC[C@H](O)CCl)Recommanded Product: 60827-45-4, and with the development of science, more effects of this compound(60827-45-4) can be discovered.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Production of (S)-3-chlorolactaldehyde from (S)-α-chlorohydrin by boar spermatozoa and the inhibition of glyceraldehyde 3-phosphate dehydrogenase in vitro, published in 1985-05-31, which mentions a compound: 60827-45-4, mainly applied to chlorolactaldehyde formation chlorohydrin sperm, Recommanded Product: 60827-45-4.

The male antifertility agent (S)-α-chlorohydrin  [60827-45-4] was metabolized by mature boar spermatozoa in vitro to (S)-3-chlorolactaldehyde  [86747-03-7]. This oxidative process, which did not occur when (R)-α-chlorohydrin was offered as a substrate, was catalyzed by an NADP-dependent dehydrogenase that converts glycerol  [56-81-5] to glyceraldehyde. (S)-3-Chlorolactaldehyde, produced by this metabolic reaction or when added to suspensions of boar spermatozoa, was a specific inhibitor of glyceraldehyde 3-phosphate dehydrogenase  [9028-92-6] as assessed by the accumulation of fructose 1,6-diphosphate and the triose phosphates. When glycerol and (S)-α-chlorohydrin were added concomitantly to boar spermatozoa in vitro, the presence of glycerol decreased the degree of inhibition of glyceraldehyde 3-phosphate dehydrogenase. Extracts of glyceraldehyde 3-phosphate dehydrogenase that were obtained from boar spermatozoa incubated with (S)-α-chlorohydrin or (R,S)-3-chlorolactaldehyde  [84709-24-0] showed significant reductions in their enzymic activity.

There is still a lot of research devoted to this compound(SMILES:OC[C@H](O)CCl)Recommanded Product: 60827-45-4, and with the development of science, more effects of this compound(60827-45-4) can be discovered.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com