Recommanded Product: (2S)-(+)-3-Chloropropane-1,2-diol. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: (2S)-(+)-3-Chloropropane-1,2-diol, is researched, Molecular C3H7ClO2, CAS is 60827-45-4, about Inhibition of glucose catabolism in rat, hamster, rhesus monkey and human spermatozoa by α-chlorohydrin. Author is Ford, W. C. L.; Harrison, Anne; Takkar, G. L.; Waites, G. M. H..
Spermatozoa from the cauda epididymis of rats treated with RS-α-chlorohydrin [96-24-2] (10 mg/kg/day for 7 days, orally) had the same ATP [56-65-5] content as control spermatozoa immediately after collection, but were unable to metabolize glucose [50-99-7] in vitro and so their ATP content declined more rapidly than that of control spermatozoa. The in vitro metabolism of glucose by spermatozoa from rat, hamster, rhesus monkey, and human was inhibited by ≥80% after 15-30 min preincubation in the presence of RS-α-chlorohydrin concentrations of <1, >10, 5-10, and >50 mM, resp. Inhibition of glucose oxidation was correlated with a reduction in ATP concentration in the spermatozoa. α-Chlorohydrin may act as an antifertility agent by inhibition of sperm glycolysis, but RS-α-chlorohydrin would apparently not be an effective contraceptive in man. However, the glucose metabolism of human spermatozoa was significantly inhibited by <10 mM of S-α-chlorohydrin [60827-45-4]. There is still a lot of research devoted to this compound(SMILES：OC[C@H](O)CCl)Recommanded Product: (2S)-(+)-3-Chloropropane-1,2-diol, and with the development of science, more effects of this compound(60827-45-4) can be discovered.
Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com