Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 59528-27-7, name is (4-Iodophenyl)methanamine hydrochloride, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C7H9ClIN
Example 2 : Obtaining the 4-iodobenzylamide of 1- pentanoylamine-cyclopentanocarboxylic acid (VI) .8.2 g (18.6 mmol) of BOP is added to a suspension of 3.96 g (18.6 mmol) of 1-pentanoylamine-cyclopentanocarboxylic acid, 5.0 g (18.6 mmol) of hydrochloride of 4- iodobenzylamine and 6.5 mL (37,2 mmol) of diisopropylamine in 40 mL of dimethylformamide, and this is stirred for 10 hr . The reaction mixture is poured onto a mixture of EtOAc (400 mL) and water (400 mL) and stirred for 30 min. Following decanting, the organic phase is washed with saturated solution of sodium bicarbonate (200 mL x 2), with 5% solution of sodium bisulphite (200 mL) , with saturated solution of sodium chloride (100 mL) , dried with magnesium sulphate and evaporated. The residue is recrystallised from 60 mL of toluene to give 6.0 g (75%) of the title compound in the form of a white solid.M. p. = 150-152CIR (KBr, cm-1) : 3340, 3280, 1660, 1650, 1540.RMN IH (DMSO-d6), delta (ppm) : 0.80 (t, 3H, CH3) , 1.10-2.20(m, 14H), 4.20 (d, 2H, CH2-Ar) , 7.05 (d, 2H, H-Ar), 7.60(d, 2H. H.Ar) .
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 59528-27-7.
Reference:
Patent; INKE, S.A.; WO2006/89927; (2006); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com