Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 629-09-4, name is 1,6-Diiodohexane, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 629-09-4
To a solution of potassium 1,3-dioxoisoindolin-2-ide (5.0 g, 26.99 mmol) in DMF (50 mL) was added 1,6-Diiodohexane (22.8 g, 67.49 mmol) and the mixture was heated at 70 C for 2.5 h. The reaction was monitored by TLC. After completion, the mixture was diluted with H2O (100 mL) and extracted with EtOAc (200 mL × 2). The combined organic layers were washed with brine (100 mL), dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure to obtain a crude which was purified by CombiFlash chromatography to afford the title compound. LC-MS 358 [M+H]+
According to the analysis of related databases, 629-09-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NUVATION BIO INC.; PHAM, Son Minh; CHAKRAVARTY, Sarvajit; CHEN, Jiyun; KANKANALA, Jayakanth; BARDE, Anup; NAYAK, Anjan Kumar; HUNG, David; (283 pag.)WO2019/222272; (2019); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com