In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 16932-44-8 as follows. Safety of 2-Iodo-1,3-dimethoxybenzene
The compound (B142, 5g18.9mmol) obtained above was dissolved in the drying THF, andthe mixture obtained by adding gradually the THF solution (9.5 mL, 2.0 M19.0mmol) ofisopropyl MAGUNE SIMM chloride at 50 degree C was stirred at the room temperature for 1hour.Next, the mixture was cooled at 78 degree C, and the phosphorus trichloride (1.3 g,9.5mmol) was added slowly. Then, the reaction intermediate containing the bis(2,6dimethoxyphenyl)phosphine chloride (B-14-4) obtained by stirring all night at the roomtemperature was used for the next reaction, without refining.
According to the analysis of related databases, 16932-44-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; JAPAN POLYETHYLENE CORPORATION; JAPAN POLYPROPYLENE CORPORATION; XIN, SHIXUAN; SHIMIZU, FUMIHIKO; SATO, NAOMASA; TANNA, AKIO; (45 pag.)JP5812764; (2015); B2;,
Iodide – Wikipedia,
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