Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 63131-30-6, name is Ethyl 3-(4-iodophenyl)-3-oxopropanoate, This compound has unique chemical properties. The synthetic route is as follows., Safety of Ethyl 3-(4-iodophenyl)-3-oxopropanoate
The reaction flask was charged sequentially with Cu (OAc) 2.H2O (0.15 mmol, 30 mg), Mg (OTf) 2 (0.2 mmol, 64 mg)DABCO (5 mmol, 560 mg), compound 1h(2 mmol, 634 mg), compound 2a (3 mmol, 342 mg), tBuONO (3 mmol, 309 mg), cyclohexane (10.0 mL).The system is then heated in the air at 80 C for about 12 hours,Extracted with ethyl acetate (40 mL x 3)The product was obtained by simple column chromatography for 3 h with a yield of 81%.The main test data obtained by the product are as follows, by analysis,The actual synthesis product is consistent with the theoretical analysis.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 63131-30-6.
Reference:
Patent; Soochow University (Suzhou); Wan Xiaobing; Chen Rongxiang; Chen Jijun; Fang Shangwen; Long Wenhao; (22 pag.)CN107445912; (2017); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com