In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 41252-96-4, name is 2-Chloro-1-iodo-4-nitrobenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. SDS of cas: 41252-96-4
General procedure: A mixture of aryl halide (1.0 mmol), PdCl2 (0.05 mmol), PPh3 (0.10 mmol), CuI (0.1 mmol) and K2CO3 (2.0 mmol) was stirred in H2O (5 mL) at room temperature under an argon atmosphere. 2-Chloro-3-propargylaminoquinoxaline (2) (1.20 mmol) was added, and the mixture stirred at 70 C for 12 h. After completion of the reaction, the resulting solution was concentrated in vacuo, and the crude residue subjected to column chromatography (silica gel) using CHCl3-CH3OH (98:2) as an eluent to afford the pure product (Table 1).
The synthetic route of 41252-96-4 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Bakherad, Mohammad; Keivanloo, Ali; Samangooei, Shahrzad; Tetrahedron Letters; vol. 53; 12; (2012); p. 1447 – 1449;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com