Electric Literature of 355-43-1, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 355-43-1 as follows.
Example 3: Synthesis of sodium perfluorohexylsulphinate: C2F5-(CF2-CF2)2-S02Na [5] 52 g (0.3 mol) of sodium dithionite (Na2S204) are added to a jacketed reactor heated using a thermostatically-controlled bath which is equipped with a mechanical stirrer, an upright reflux condenser, a dropping funnel and a temperature probe and which contains 16 g (0.15 mol) of sodium carbonate (Na2C03) dissolved in 480 g of demineralized water. After dissolution, 89.2 g (0.2 mol) ofC6F131, in solution in 120 g of ethanol, are added thereto dropwiseover ‘/2 hour; the two-phase mixture obtained is brought to reflux (76 C) for 1h 30, giving a homogeneous colourless solution. After cooling, this solution is poured onto 180 g of ethyl acetate and 400 g of a saturated aqueous NaCl solution. After separating by settling, the organic phase is washed with a saturated NaCl solution and dried over Na2S04. The solvent is subsequently removed by distillation on a rotary evaporator under reduced pressure. The white solid recovered (79 g, Yd 97%) isC6F13S02Na [5] (MS/negative electrospray: peak at 383 = C6F13SO2-; NMR purity 97%).
According to the analysis of related databases, 355-43-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ARKEMA; WO2005/121060; (2005); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com