In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 618-91-7, name is Methyl 3-iodobenzoate belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C8H7IO2
General procedure: To a mixture of Iodobenzene (1.0 mmol), styrene (1.2 mmol), NaOAc (1.5 mmol), Catalyst (0.007 mmol) and DMF (3mL) was added in round bottom flask. (No inert gas protection was needed.). The reaction was carried out at 120 C for 15 min. Upon completion of reaction as indicated by TLC, the reaction mixture was poured in crushed ice-water, extracted with ethyl acetate, dried over anhydrous Na2SO4, concentrated in vacuum to give crude product which was purified through column chromatography on silica gel (100-200) to afforded pure stilbenes in 90-98% yields.
The synthetic route of 618-91-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Sharma, Sonam; Sarkar, Bibhas R.; Synthetic Communications; vol. 48; 8; (2018); p. 906 – 914;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com