Related Products of 26059-40-5, The chemical industry reduces the impact on the environment during synthesis 26059-40-5, name is 2-(2-Iodophenyl)ethan-1-ol, I believe this compound will play a more active role in future production and life.
Aryl iodide 9 (1.15 g, 4.63 mmol) and stannane 183 (2.08 g, 6.98 mmol) were dissolved in toluene (15 mL) under argon. The solution was degassed for 10 minutes. Pd2(dba)3 (430 mg, 0.47 mmol) was added at room temperature, followed by P(t-Bu)3 (112 mg, 0.55 mmol, 10% in hexane). The reaction was heated at 80 C and stirred for 12 hours at that temperature. After cooling at room temperature, the solution was filtered through a silica plug and concentrated under reduced pressure. Silica gel flash chromatography provided alcohol 19 as oil (963 mg, 68%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(2-Iodophenyl)ethan-1-ol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Fischer, Derek; Nguyen, Thong X.; Trzoss, Lynnie; Dakanali, Marianna; Theodorakis, Emmanuel A.; Tetrahedron Letters; vol. 52; 38; (2011); p. 4920 – 4923;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com