Adding a certain compound to certain chemical reactions, such as: 82998-57-0, name is 3-Iodo-4-methylbenzoic acid, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 82998-57-0, Computed Properties of C8H7IO2
3-Iodo-4-methylbenzoic acid (1.28 g, 4.88 mmol) was suspended in DCM (25 mL). Oxalyl chloride (420 muL, 4.9 mmol) was added, followed by DMF (1 drop). The reaction was stirred at 22 C., and gas evolution was observed for around 60 minutes, at which point HPLC analysis indicated almost complete consumption of the starting material. The solvent was removed under vacuum to provide 1.38 g (101% yield) of orange oil that solidified on storage. This material was used in the next step without further purification or characterization.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Iodo-4-methylbenzoic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Promega Corporation; Levin, Sergiy; Ohana, Rachel Friedman; Kirkland, Thomas; Wood, Keith V.; (117 pag.)US2016/355523; (2016); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com