Synthetic Route of 61272-76-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 61272-76-2, name is 4-Fluoro-2-iodoaniline, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: To the solution of o-iodoaniline derivatives (1.00 mmol) in pyridine methanesulfonyl chloride (1.00 mmol) was added and the reaction mixture was stirred at r.t. for 2 h. Water (100 ml) was then added, and the solution was extracted with ethyl acetate (3 x 10 ml). The organic extracts were washed with water (4 x 50 ml) and brine (50 ml), dried over Na2SO4 and the solvent was distilled off to furnish a viscous mass that was purified by column chromatography on silica gel to get compound 17
The chemical industry reduces the impact on the environment during synthesis 4-Fluoro-2-iodoaniline. I believe this compound will play a more active role in future production and life.
Reference:
Article; Debnath, Sudarshan; Mondal, Shovan; Tetrahedron Letters; vol. 59; 23; (2018); p. 2260 – 2263;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com