Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 689260-53-5, name is 2-Bromo-5-iodo-1,3-dimethylbenzene, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C8H8BrI
Under an argon atmosphere, Intermediate 6 (1.20 g, 2.40 mmol), 2-Bromo-5-iodo-1,3-dimethylbenzene (Intermediate 15) (893 mg, 2.88 mmol)(1.68 g, 4.80 mmol, manufactured by Wako Pure Chemical Industries, Ltd.) and copper iodide (91.4 mg, 0.48 mmol, 0.35 mmol) were added to a solution of L-proline (110 mg, 0.96 mmol; manufactured by Wako Pure Chemical Industries, (Manufactured by Wako Pure Chemical Industries, Ltd.) Dimethylformamide (2.4 ml, manufactured by Wako Pure Chemical Industries, Ltd.) was heated to 110 C under an argon atmosphere for 48 hours. to the next,After cooling to room temperature, saturated aqueous ammonium chloride solution (30 ml) and dichloromethane (100 ml) were added to the reaction mixture and the layers were separated. The organic layer was dried over magnesium sulfate and the residue was purified by silica gel column chromatography (dichloromethane 20% Hexane 80%) to obtain Intermediate 16 as pale yellow crystals (1.49 g, yield 91%).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 689260-53-5.
Reference:
Patent; Kokuritsu Daigaku Hojin Kyushu Daigaku; Kaji, Hironori; Suzuki, Hajime; Suzuki, Katsuaki; Oheiwa, Hajime; Wakamiya, Atsushi; Fukushima, Tatsuya; Suzuki, Huritz; Murata, Yaseujiro; Sieje, Kacheuyuki; Adachi, Jihaya; (48 pag.)KR2015/123907; (2015); A;,
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