Application of 76801-93-9, These common heterocyclic compound, 76801-93-9, name is 5-Amino-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
compound of formula [2] 5-amino-2,4,6-triiodo-N,N’-bis(2,3-dihydroxypropyl)-1,3-phthalamideReacts with acetic anhydride,The temperature is raised to 65 C -70 C for 2-6 hours, and the TLC monitoring reaction is completed.Concentrated under reduced pressure to obtain a compound of the formula [3]5-acetamido-2,4,6-triiodo-N,N’-bis(2,3-diacetoxypropyl)-1,3-phthalic acid amide;
Statistics shows that 5-Amino-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide is playing an increasingly important role. we look forward to future research findings about 76801-93-9.
Reference:
Patent; Tianjin Heqing Chemical Co., Ltd.; Liu Guoping; Li Yi; (7 pag.)CN108191690; (2018); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com