Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 626-44-8, name is 1,3,5-Triiodobenzene, A new synthetic method of this compound is introduced below., Computed Properties of C6H3I3
1,3,5-triiodobenzene (33.0 g, 0.10 mol), Pd(dppf)Cl2.CH2Cl2 (700 mg, 0.86 mmol) under nitrogen atmosphereCuI (330 mg, 1.73 mmol) and isopropylamine (60 ml) were added to tetrahydrofuran (400 ml), and stirred at room temperature for 10 min.Trimethylsilylacetylene (32.3 g, 0.33 mol) was slowly added by syringe, and the mixture was warmed to 80 ° C and stirred for 12 hours.TLC showed the end of the reaction, and a silica gel column (PE/EA = 4/1 to 2/1) gave Compound 11 (33.0 g, yield 90percent).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Shanghai Hehui Optoelectric Co., Ltd.; Wu Fan; (24 pag.)CN108530431; (2018); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com