Adding a certain compound to certain chemical reactions, such as: 175278-00-9, name is 1-Iodo-2-(trifluoromethoxy)benzene, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 175278-00-9, HPLC of Formula: C7H4F3IO
General procedure: A sealed tube containing a magnetic stirring bar was charged with aryl iodide (1.0 mmol), Te (0.13 g, 1.0 mmol), KOH (0.11 g, 2.0 mmol) and DMSO (2 mL) under nitrogen. The reaction mixture was heated in an oil bath at 110 C and stirred at this temperature for 10 h. The progress of the reaction was monitored by TLC via syringe. After the reaction was complete, the reaction mixture was allowed to cool, and treated with CH2Cl2 and H2O. The organic layer was washed with sat. NH4Cl and brine solution, dried with Na2SO4 and concentrated under vacuum. The residue was purified by column chromatography on silica gel with an eluent consisting of hexanes and ethyl acetate to affording the corresponding diaryl tellurides in good yields.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Iodo-2-(trifluoromethoxy)benzene, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Zhang, Shaozhong; Kolluru, Lalitha; Vedula, Souseelya K.; Whippie, Drew; Jin, Jin; Tetrahedron Letters; vol. 58; 37; (2017); p. 3594 – 3597;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com