Related Products of 19094-56-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 19094-56-5, name is 2-Chloro-5-iodobenzoic acid belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: The 25-OCH3-PPD (1 equiv) was added to a solution of DCC (2 equiv), DMAP (0.2 equiv) and different aromatic groups (1 equiv) in dry dichloromethane and the reaction mixtures were shaken for 24 h. The solvent was removed under reduced pressure to give a white solid. The white solid was dissolved in ethyl ether and washed with NaHCO3 (5%), dried (MgSO4) and concentrated under reduced pressure to give the crude product. The crude products were chromatographed by silica gel and eluted with petroleum ether/ethyl acetate (4:1, 2:1 and 1:1) to give the pure products 1b, 1c and 1a. Using the same procedure described above for the other compounds.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Chloro-5-iodobenzoic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Qu, Fan-Zhi; Xiao, Sheng-Nan; Wang, Xu-De; Zhang, Yan; Su, Guang-Yue; Zhao, Yu-Qing; Bioorganic and Medicinal Chemistry Letters; vol. 29; 2; (2019); p. 189 – 193;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com