Related Products of 104539-21-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 104539-21-1 name is 1-Iodo-2-(2-methoxyethoxy)ethane, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: Individual solutions of N-(trimethylsilyl)methyl-N-benzylamine (15.5 mmol) in MeCN (100 mL) containing K2CO3 (31 mmol) and alkyl halide (30 mmol of 1-hexyl bromide, 2-(2-methoxyethoxy)ethyl iodide, ethyl 2-bromopropionate) were stirred for 12 h at room temperature and concentrated in vacuo to give residues that were triturated with CH2Cl2. The triturates were dried and concentrated in vacuo to afford residues, which were subjected to column chromatography (EtOAc: Hex=1: 8) to yield 19 (81 %), 22 (90 %) and 23 (44 %).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-Iodo-2-(2-methoxyethoxy)ethane, and friends who are interested can also refer to it.
Reference:
Article; Lim, Suk Hyun; Cho, Dae Won; Mariano, Patrick S.; Tetrahedron; vol. 74; 3; (2018); p. 383 – 391;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com