In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 31599-61-8 as follows. SDS of cas: 31599-61-8
General procedure: In a typical experiment the catalyst (containing 2.8 lmol Pd) was placed in a stainless steel autoclave. The aryl iodide (0.2 mmol), amine (0.5 mmol), base (35 ll, 0.25 mmol) and solvent (1 ml) were transferred into it under an inert atmosphere. It was charged with carbon monoxide (30 bar or 5 bar) and heated with stirring in an oil bath at 100 C or 120 C. After cooling to room temperature the catalyst was removed by filtration and was reused without further purification if the product was soluble in the solvent. In other cases, the solid material was washed by acetone and the catalyst was dried in vacuo prior to reuse. The reaction mixture was analyzed by gas chromatography.
According to the analysis of related databases, 31599-61-8, the application of this compound in the production field has become more and more popular.
Reference:
Article; Urban, Bela; Skoda-Foeldes, Rita; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 194; 4-6; (2019); p. 302 – 306;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com