Adding a certain compound to certain chemical reactions, such as: 627-31-6, name is 1,3-Diiodopropane(stabilized with Copper chip), belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 627-31-6, Formula: C3H6I2
General procedure: A suspension of alkenyl- or aryl-dithiol(1.0 mmol), triethylamine (2.0 mmol), LR (0.44g, 1.0 mmol) or FcLR (0.56 g, 1.0 mmol) and dihaloalkane(1.0 mmol) in dry THF (60 mL) was stirred under N2 gas atmosphere at ambient temperature for 24 h leadingto a reddish yellow or pale-yellow suspension. Upon filtering to remove insoluble solid the filtrate was driedunder reduced pressure. The residue was dissolved in dichloromethane (ca. 2 mL) and was loaded onto a silicagel column (dichloromethane as eluent) to give the macrocycles. Another unexpected nine-membered ring 4was also obtained in respective 25% and 30% yields in the cases of 5 and 9. Two diastereomers wereseparated completely in the cases of 10 and 12.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1,3-Diiodopropane(stabilized with Copper chip), and friends who are interested can also refer to it.
Reference:
Article; Hua, Guoxiong; Cordes, David B.; Slawin, Alexandra M. Z.; Woollins, J. Derek; Synlett; vol. 29; 11; (2018); p. 1496 – 1501;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com