These common heterocyclic compound, 627-32-7, name is 3-Iodo-1-propanol, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Application In Synthesis of 3-Iodo-1-propanol
The 1900g (10.22 muM) 3 – iodo propanol, 20g sulfuric acid are added to a reaction container, access oxirane 200g (4.50 muM), to maintain the reaction temperature 25 C the left and the right, reaction finishes rectification, to obtain the colorless liquid 1 – glycol ether propyl iodide 721g, the purity is greater than 95%, yield 69%, the structure of the characterization as shown in the following data.
The synthetic route of 3-Iodo-1-propanol has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Henan Longdou Petrochemical Co., Ltd.; Xu Bo; Zhuang Guanghai; Feng Wei; Zhuang Guoyin; Dong Xuekun; Guo Libing; (5 pag.)CN106554261; (2017); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com