Reference of 191348-14-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 191348-14-8, name is 2-Iodo-4-methoxyaniline, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: A mixture of O-phenylpropynyl sugar aldehyde (1 mmol)and substituted aniline (1 mmol) in DCE (5 mL) was stirred for 4 h at roomtemperature in the presence of Ph3PAuCl (10 mol %)/AgSbF6 (10 mol %). Aftercomplete conversion as monitored by TLC, the mixture was concentrated invacuo and purified by silica gel column chromatography using ethyl acetate-hexane (2:8) as eluent to afford the pure product. The spectral data can be found Supplementary data.
The chemical industry reduces the impact on the environment during synthesis 2-Iodo-4-methoxyaniline. I believe this compound will play a more active role in future production and life.
Reference:
Article; Reddy, B.V. Subba; Majumder, Nilanjan; Sridhar; Tetrahedron Letters; vol. 55; 44; (2014); p. 6081 – 6084;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com