Related Products of 3058-39-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3058-39-7, name is 4-Iodobenzonitrile belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: Phenylpropiolic acid (43.8 mg, 0.3 mmol), iodobenzene (61.2 mg, 0.3 mmol), Na2CO3 (47.6 mg, 0.45 mmol), NaCuY (12 mg, 0.03 mmol) were added to a vial under DMSO (1.0 mL). The resulting mixture was heated to 100 °C for 12 h under vigorous stirring. After complete reaction, the reaction mixture was treated with water and extracted with EtOAc. The organic layer was dried under MgSO4 and concentrated by using vacuum evaporation. The crude mixture was purified by column chromatography.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Iodobenzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Park, Jaerim; Jung, Dasom; Kim, Han-Sung; Na, Kyungsu; Lee, Sunwoo; Catalysis Communications; vol. 99; (2017); p. 83 – 88;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com