42861-71-2, name is 3-Iodophenyl acetate, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. name: 3-Iodophenyl acetate
Step 1: 3-{(6-[4-(2-Trifluoromethylbenzoyl)piperazin-l-yl]pyridazin-3-yl)ethynyl}- phenyl acetate: Prepared by Sonogashira coupling reaction of Intermediate 6 with 3-iodophenyl acetate in a mixture of triethylamine and DMSO to give the product as an off-white solid; IR (KBr) 2926, 2216, 1640, 1434, 1316, 1116, 1010, 785 cm”1; 1H NMR (300 MHz, CDCl3) delta 2.31 (s, 3H), 3.29-3.86 (m, 2H), 3.70-4.10 (m, 6H), 6.90 (d, J= 9.9 Hz, IH), 7.11 (d, J= 7.2 Hz, IH), 7.32-7.76 (m, 8H); ESI-MS (m/z) 454.88 (M)+.
The synthetic route of 42861-71-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; GLENMARK PHARMACEUTICALS S.A.; WO2008/62276; (2008); A2;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com