Reference of 35453-19-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 35453-19-1, name is 5-Amino-2,4,6-triiodoisophthalic acid belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
The product (S2) obtained in the step 1) of Example 2, 3,5-dicarboxy(2,4,6)triiodoaniline (10 g, 0.018 mol) was dissolved in 40 mL of ethyl acetate.60 mL of SOCl2 (8.6 g, 0.072 mol) was slowly added dropwise at 70 C.(The purpose of the dropping control temperature does not exceed 10 C), after the addition is completed, the temperature is raised to 80 C,The reaction was refluxed for 20 h, and about half of the solvent was distilled off.Allow to stand for 2 hours, filter, and dry (85 C drying to moisture content ? 1.5%),A brownish brown powdery compound (S3) was obtained.
The synthetic route of 5-Amino-2,4,6-triiodoisophthalic acid has been constantly updated, and we look forward to future research findings.
Reference:
Patent; China Calculate University; Wu Zhiping; Bai Xueyan; Wu Yuqi; (13 pag.)CN108727376; (2018); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com